The Investigator Casework GO! Kit is used for the pretreatment of forensic samples in a direct amplification workflow. The kit permits sample lysis without DNA purification and the lysate is compatible with several downstream options, including the Investigator Quantiplex Pro and Quantiplex Pro RGQ or the Investigator 24plex QS, ESSplex SE QS or IDplex Plus Kits.
The Investigator Casework GO! Kit can be used for direct amplification of casework samples and thus enables an accelerated workflow in casework analysis. It allows the rapid processing of swabs from casework samples, including cuttings of sexual assault swabs, or other materials, without the need for further purification. The lysate can be used directly for quantification with all Investigator Quantiplex assays or for DNA profiling using all Investigator STR assays (unless data from the quantification indicates presence of possible PCR inhibitors).
In sexual assault screening analyses, the Investigator Casework GO! workflow can facilitate sample processing decisions by male-quantification and Auto/Y ratio.