EpiTect Methyl II PCR Assay detects methylation in heterogeneous samples.
EpiTect Methyl II PCR Assay detects methylation in heterogeneous samples.
EpiTect Methyl II PCR Arrays verify breast cancer gene methylation status in breast cancer cell lines.
EpiTect Methyl II PCR Arrays verify breast cancer gene methylation status in breast cancer cell lines.
EpiTect Methyl II PCR Assay detects methylation in heterogeneous samples. Analytical sensitivity was tested using a serial dilution of SKBR3 genomic DNA and peripheral blood leukocyte genomic DNA. Using Human HIC1 DNA EpiTect Methyl II PCR Primers, the percentage of methylated HIC1 relative to the total amount of input DNA was detectable even down to only 6% of the total DNA sample. The HIC1 gene promoter is methylated in cancer cells and unmethylated in normal cells.
EpiTect Methyl II PCR Arrays verify breast cancer gene methylation status in breast cancer cell lines.

The heat map compares the methylation status of genes in the genomic DNA of 3 breast cancer cell lines and blood genomic DNA (control), as determined by the Human Breast Cancer Signature Panel EpiTect Methyl II PCR Arrays.