Mouse tail samples were treated with 180 µl Buffer ATL and 20 µl QIAGEN Proteinase K at 56°C overnight. Genomic DNA was purified from the lysed tissue samples using the BioSprint 96 DNA Blood Kit with the BioSprint 96 DNA Tissue protocol. DNA was eluted in 200 µl elution buffer. Eluates (2 µl) from 8 out of 96 samples were visualized by agarose gel electrophoresis. M: markers.