Special considerations in preparing circulating cell-free DNA samples

How are your ccfDNA yields? Purifying ccfDNA can be very challenging, but it doesn’t have to be. In this webinar, we will address how you can ensure your success by avoiding the 5 key pitfalls in ccfDNA sample preparation:

Isolation of blood with the wrong blood collection tube
Inadequate sample transportation or storage concept
Centrifugation parameters not optimized for plasma separation
Extraction method that is cumbersome or inappropriate
Suboptimal method for quality control and yield quantification

Join us and learn how to overcome these challenges to ensure optimal preparation of a high quality and quantity of ccfDNA.

Dr. Daniel Groelz, Scientific Associate Director R&D, QIAGEN GmbH


Dr. Daniel Groelz is a Scientific Associate Director of Research and Development at QIAGEN in Hilden, Germany. Dr. Groelz is the R&D project manager who led an international team within PreAnalytiX GmbH to develop the PAXgene Tissue System. He was the leader for the evaluation of the PAXgene Tissue System within the European collaborative grant project, SPIDIA, and is currently managing work packages in two other grant projects to evaluate the PAXgene Tissue System for NGS applications and use in routine pathology workflows.

Prior to joining QIAGEN, Dr. Groelz worked for Autoimmun Diagnostika GmbH in Albstadt, Germany. Dr. Groelz received a Ph.D. in Biology from the University of Mainz with a concentration in Physiological Chemistry. He is the main inventor of the PAXgene Tissue System and he is an inventor/co-inventor on three other patent families.