Automation quality control mainvisual tools
  • Main Image Navi
LNA-enhanced oligonucleotides have different thermodynamic properties from traditional DNA oligonucleotides and will thus fold differently.

The LNA Oligo Optimizer calculates scores for self-complementarity and secondary structure of an LNA-enhanced oligonucleotide. These scores can be used as a rough estimate of the temperature at which an oligonucleotide will form secondary structure and self-complementarity.

Please use this base code:
  • DNA bases: A, C, G, T
  • Locked nucleic acid bases (LNA) are entered as '+' followed by the base (example: +A)
Note! The bases require to be entered in UPPERCASE!

Hybridizations with scores smaller than that won't be shown
Hybridizations with scores bigger than that won't be shown