Advancing microbiome research
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Microbiome

Advancing microbiome research

From the human gut to varied environments such as antarctic soil, ocean water, or acidic hot spring biofilms, microbiome can be found in diverse conditions. Regardless of the origin of the sample, microbiome researchers require high yields and unbiased results to analyze microbial communities. But researchers often face complex and difficult-to-lyse samples. Furthermore, inhibitors present in these samples and background DNA and RNA can cause inaccurate quantification of nucleic acids and may inhibit downstream applications.

QIAGEN offers a broad range of manual and automation-friendly solutions to help microbiome researchers overcome challenges and to advance microbiome research. From Sample to Insight, get results you can trust.

From microbes to microbiomes
From challenging samples to insights

From challenging samples to insights

To drive insights in the exciting field of microbiome, we have applied our extensive experience in developing dedicated products along the complete workflow. From sample disruption to nucleic acid isolation to PCR and NGS to digital insights – we provide the most robust technologies for microbiome analysis to spur your research breakthroughs.

QIAGEN’s microbiome Sample to Insight workflows for human biomedical, environmental and agricultural research provide proven, reliable and dedicated microbiomics solutions that address the specific demands of every step of the workflow to gain accurate and unbiased results.

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Get a complete workflow overview
Check out the complete workflow for microbiome research.

Figuring out how microbes run the world

Metagenomics, also known as community genomics, is the study of genetic material to characterize microbial systems. It provides scientists with a means to study microbes, which cannot be cultured and an alternative to the genetic homogeneity that is a hallmark of pure culture. Metagenomics enables scientists to better capture the microbiome diversity, and in this way, to better understand both our physiology and the systems of the world we live in. Dive into the existing field of Metagenomics by reading our 3-part article series.

Figuring out how microbes run the world
"We get really good results using the QIAGEN DNA kits, with high DNA yields, which can be used for sequencing."
Dr. Hannah Wardill, Biomedical Research Fellow, University of Groningen and University of Adelaide
Go beyond the limits of real-time PCR
Explore digital PCR for higher accuracy, sensitivity and quantification.

Automated solutions to standardize your microbiome workflow

Sample preparation is a significant factor in determining the success of every microbiome workflow and its reproducibility. Variations in nucleic acid quality, like degradation, concentration, or presence of contaminants, can impact your results and their interpretation. Extraction of nucleic acids by different users allows for increased chances of error due to multiple manual interventions. This further leads to irregularities in the research outcome. Automating the extraction of nucleic acids is one way to ensure reproducibility. Learn more about QIAGEN’s automated solutions for standardized and reproducible sample processing.

Microbiome FAQs

What is the microbiome?

The microbiome is the community of microorganisms (bacteria, archaea, fungi, viruses and eukaryotes) that can be found inside and on the human and animal body, as well as on plants and in the environment.

What is metagenomics?

Metagenomics, also known as community genomics, is the genetic analysis of microbial communities contained in natural living environments. It enables the analysis of the microbial diversity and ecology of a specific environment. Metagenomics provides scientists with a means to study microbes which cannot be cultured and enables them to better capture the extraordinary diversity present within microbial communities. This is achieved by Next-Generation Sequencing techniques with the ability to analyse thousands of samples in parallel. Scientists can then gain valuable insights to better understand both our own physiology and the systems of the world we live in.

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