The REPLI-g Single Cell RNA Library Kit provides a complete WTA workflow – from cell lysis, gDNA removal and cDNA synthesis to highly uniform amplification across the entire transcriptome in a one-tube protocol – with negligible sequence bias. This is followed by fast, one-tube library construction without cleanup steps between different enzymatic reactions.
Sequencing libraries were generated from 3 individual HeLa S3 cells using the REPLI-g Single Cell RNA Library Kit and sequenced on an Illumina sequencer. The plot shows the number of genes detected in each single cell.
RNA-Seq libraries were prepared in triplicate from 1 or 10 HeLa S3 cells and in duplicate from 25 HeLa S3 cells using the REPLI-g Single Cell RNA Library Kit, and sequenced on an Illumina platform. The percentage of RNA biotypes detected in each library is plotted.
RNA-Seq libraries were prepared from 1, 3, 10, 25 or 50 HeLa S3 cells using the REPLI-g Single Cell RNA Library Kit and sequenced on an Illumina platform.