Paving the way for liquid biopsy
Innovation for progress
To drive the adoption of liquid biopsy in clinical and research laboratories, we have applied years of experience in the field to develop a dedicated Sample to Insight workflow. From sample collection to data interpretation – we provide the most robust technologies and resources to help you discover, detect and validate biomarkers for all three emerging liquid biopsy approaches: circulating cell-free nucleic acids, CTCs and exosomes.
Across analytesWe develop proven technologies to stabilize, extract and analyze circulating cell-free nucleic acids, exosomes and CTCs from blood, urine and other biofluids.
Across fieldsWe are committed to working with researchers, pathologists and clinicians to ensure that today’s biomarker discoveries become tomorrow’s clinical breakthroughs.
Across technologiesWe use advanced chemistries, sequencing technologies, automated platforms and interpretation tools to ensure you get meaningful results from your liquid biopsy samples.
Across workflowsWe create robust Sample to Insight solutions to offer you a broad portfolio of tools to improve standardization, sensitivity and specificity at every step of your workflow.
Latest – Get news, updates and stories
Expert’s view on the advances and challenges of liquid biopsyInterview with Prof. Klaus Pantel
Multi-analyte analysis gives more insights from less sampleInterview with Dr Corinna Keup
Collaborations help bring promise of liquid biopsy to routine clinical practiceInterview with Prof. Klaus Pantel and Dr. Thomas Schlange
A Sample to Insight liquid biopsy workflow
Sample collection & stabilizationEnsure long-term stability of markers and eliminate analysis errors caused transportation and storage.
Sample preparationAchieved the highest yield and purity of circulating nucleic acids, exosomes and CTCs.
NGS & PCR analysisFocus on relevant markers and gene expression signatures with targeted sequencing and validated PCR assays.
Data analysisIdentify low-frequency variants and determine changes in expression with high accuracy.
Data interpretationGenerate biological hypotheses and uncover the significance of ‘omics data to identify new targets or candidate biomarkers.
Featured – Dive deeper into liquid biopsy
GuideMaximize your miRNA profiling success using advanced NGS and PCR technologies.
Webinar SeriesDiscover innovations to isolate mRNA and miRNA from urinary exosomes and other biofluids.
VideosHear expert answers to top FAQs on liquid biopsy challenges & clinical application.
Explore our Cancer Research Hub
Accelerate your journey to insights and help conquer cancer
FAQs – Quick answers and insights
What is a liquid biopsy?
A quick, non-invasive procedure that limits the need for surgical biopsy. It allows biomarkers for diseases such as cancer to be discovered in biofluids such as blood and urine, allowing for better disease detection and management. We offer a comprehensive portfolio of solutions in the field of liquid biopsy solutions covering the most important analytes: circulating tumor cells, exosomes and circulating cell-free nucleic acids.
What are the advantage and challenges of liquid biopsy?
Liquid biopsies can be useful when a tissue sample is limited or hard to reach and if regular monitoring is needed. The main challenges include: detecting a low amount of analytes in a high background and a lack of standardization. To overcome these, we have developed a comprehensive portfolio of liquid biopsy solutions to meet your changing needs.
- PAXgene technology for reliable sample collection and stabilization
- Optimized sample preparation kits for isolating ccfDNA, ccfRNA, exosomes and CTCs from various biofluids
- QIAseq solutions for NGS analysis
- Predesigned or custom arrays and panels for PCR-based analysis
- Genomics Workbench for accurate data analysis